Here’s some science, courtesy of University of Southern California researchers, to back up claims that cannabis users show decreased levels of depression. Rolling Stone looks at another academic study that explores how cannabis may play a role in how humans experience emotions and mood.

However, when it comes to anxiety and depression, once again the evidence points to the importance of keeping THC levels down. Testing suggests that low levels of THC are actually beneficial in helping manage anxiety and depression; studies show that it is only after a certain threshold is passed that problems occur.